Mechanisms of PARP inhibitor resistance in cancer and insights into the DNA damage response
Editorial summary Inhibitors of poly(ADP-ribose) polymerase (PARPi) have entered the clinic for the iphone 13 pro max price florida treatment of patients with cancers that lack homology-directed DNA repair, but drug resistance remains a houston texans shorts clinical hurdle.Recent advances in the identification of PARPi resistance mechanisms have y